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Life and death at the heart of Boston bombing trial

Courtroom sketch shows Boston Marathon bombing suspect Tsarnaev during the jury selection process in his trial at the federal courthouse in BostonBy Scott Malone BOSTON (Reuters) - From the moment U.S. prosecutors stand up on Wednesday and begin their case against accused Boston Marathon bomber Dzhokhar Tsarnaev, their minds and those of their defense counterparts will be focused on just one thing: The death penalty. Tsarnaev, 21, is accused of killing three people and injuring 264 with a pair of homemade pressure-cooker bombs left at the race's crowded finish line on April 15, 2013, in the largest mass-casualty attack on U.S. soil since Sept. 11, 2001. "The bottom line is you're not going to get a not guilty in this case," said Jules Epstein, a Widener University School of Law professor who has represented defendants in federal and Pennsylvania death penalty cases. So every move is with an eye on the end game and that is avoiding death." Tsarnaev has pleaded not guilty to all charges and his attorneys have offered little detail on their case, with the bulk of both prosecution and defense filings under seal in Boston federal court.


Spotify's Top 10 most viral tracks

FILE - This May 18, 2013 file photo shows Hannah Hooper, left, and Christian Zucconi of Grouplove performing as part of Party in the Park at Centennial Olympic Park in Atlanta. Grouplove's, “Ways to Go,” was the most viral track on Spotify, from Monday, June 10, to Sunday, June 16, via Facebook, Tumblr, Twitter and Spotify. (Photo by Robb D. Cohen/RobbsPhotos/Invision/AP, file)The following list represents the most viral tracks on Spotify, based on the number of people who shared it divided by the number who listened to it, from Monday, Oct. 20 to Sunday, Oct. 26 via Facebook, Tumblr, Twitter and Spotify.


Amgen says Kyprolis doubles progression-free survival vs Velcade
Amgen Inc's Kyprolis helped patients with relapsed multiple myeloma live twice as long before their blood cancer worsened compared to a regimen containing rival drug Velcade, according to an interim analysis announced by the company on Sunday. Kyprolis, the centerpiece of Amgen's nearly $10 billion acquisition of Onyx Pharmaceuticals in 2013, had sales last year of $331 million. Velcade, sold by Takeda Pharmaceutical Co and Johnson & Johnson, had 2014 sales of nearly $3 billion. The interim look showed that patients with relapsed multiple myeloma treated with Kyprolis and chemotherapy dexamethasone lived for a median of 18.7 months before their disease worsened, compared with 9.4 months for patients treated with Velcade and the chemotherapy drug.
Homeland Security funding drama darkens U.S. fiscal outlook

In this Feb. 27, 2015, photo, House Democratic Leader Nancy Pelosi of Calif., accompanied by House Minority Whip Steny Hoyer of Md., voice their objections to the Republican majority during a delay in voting for a short-term spending bill for the Homeland Security Department during a news conference on Capitol Hill in Washington. Democrats didn’t get all they wanted in Congress’ struggle over Homeland Security, but many feel they are winning a broader political war that will haunt Republicans in 2016 and beyond. "It’s a staggering failure of leadership that will prolong this manufactured crisis of theirs and endanger the security of the American people," said Pelosi. (AP Photo/J. Scott Applewhite)By Richard Cowan and David Lawder WASHINGTON (Reuters) - Congress narrowly averted a partial shutdown of the U.S. domestic security agency late on Friday night, but the forces behind the chaotic episode remain - fractious Republicans and House Speaker John Boehner's lack of control over them. In five to seven months, the federal debt ceiling will again be reached, and by October Congress must pass spending bills to keep the government running in the new fiscal year. Failing to deal effectively with these issues could have much more damaging repercussions - such as a broad government shutdown or a debt default - than a partial shutdown of the Department of Homeland Security (DHS). Some conservatives speak of ousting Boehner, but it is unlikely they can muster enough votes, while others made clear on Friday that they were willing to take big risks to score ideological points.     Brinkmanship like this, reminiscent of 2013's 16-day federal government shutdown, was supposed to be over.


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